Description
Triglypta-M 500 is a triple-combination antidiabetic formulation containing Dapagliflozin 10 mg, Sitagliptin 100 mg and Metformin Hydrochloride 500 mg. It is prescribed for the management of Type 2 Diabetes Mellitus in patients who require combination therapy.
The three active ingredients work through different but complementary mechanisms to support blood glucose management. The medicine should be used along with appropriate diet, physical activity and lifestyle measures as advised by a healthcare professional.
Composition
Each tablet contains:
- Dapagliflozin – 10 mg
- Sitagliptin – 100 mg
- Metformin Hydrochloride – 500 mg
Dosage Form: Tablets
Uses and Indications
Triglypta-M 500 may be prescribed for:
- Management of Type 2 Diabetes Mellitus
- Improving blood glucose control
- Supporting glycemic management when combination therapy is required
- Patients requiring therapy involving an SGLT2 inhibitor, DPP-4 inhibitor and Metformin
- Supporting overall diabetes management along with diet and exercise
The medicine should be taken strictly according to the prescription of a qualified healthcare professional.
Benefits of Dapagliflozin + Sitagliptin + Metformin
This triple combination provides complementary approaches to blood glucose management:
- Helps improve glycemic control
- Combines three different antidiabetic mechanisms
- Supports glucose regulation through multiple pathways
- Metformin helps improve insulin sensitivity
- Sitagliptin supports glucose-dependent insulin secretion
- Dapagliflozin increases urinary glucose excretion
How Does Triglypta-M 500 Work?
Dapagliflozin
Dapagliflozin is an SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, increasing urinary glucose excretion and helping lower blood glucose levels.
Sitagliptin
Sitagliptin is a DPP-4 inhibitor. It increases the activity of incretin hormones, supporting glucose-dependent insulin secretion and helping regulate glucagon.
Metformin
Metformin primarily decreases glucose production by the liver and improves the body’s sensitivity to insulin.
Together, these medicines offer complementary mechanisms for managing blood glucose in suitable patients with Type 2 Diabetes.
Dosage and Administration
The dosage of Triglypta-M 500 should be determined by the treating physician based on the patient’s blood glucose control, kidney function, medical history and current medications.
Take the medicine exactly as prescribed. Do not change the dosage or discontinue treatment without consulting your doctor.
Possible Side Effects
Possible side effects may include:
- Nausea
- Diarrhea
- Stomach discomfort
- Headache
- Increased urination
- Urinary tract infections
- Genital infections
- Dizziness or dehydration
If side effects are severe or persistent, consult a healthcare professional.
Precautions
Before taking Dapagliflozin, Sitagliptin and Metformin Hydrochloride Tablets, inform your doctor about your medical history and all medicines you are currently taking.
Patients with kidney problems, dehydration or other relevant medical conditions may require special evaluation before and during treatment.
Triglypta-M 500 is a prescription medicine and should be used only under medical supervision.
Product Details
| Parameter | Details |
|---|---|
| Brand Name | Triglypta-M 500 |
| Composition | Dapagliflozin 10 mg + Sitagliptin 100 mg + Metformin HCl 500 mg |
| Dosage Form | Tablets |
| Therapeutic Category | Antidiabetic |
| Indication | Type 2 Diabetes Mellitus |
| Prescription | Prescription Medicine |
| Pack Size | As per approved product pack |
| Marketer | Rapid Life Drugs & Healthcare |
Frequently Asked Questions
1. What is Triglypta-M 500?
Triglypta-M 500 is a triple-combination antidiabetic tablet containing Dapagliflozin 10 mg, Sitagliptin 100 mg and Metformin Hydrochloride 500 mg.
2. What is the composition of Triglypta-M 500?
Each tablet contains Dapagliflozin 10 mg + Sitagliptin 100 mg + Metformin Hydrochloride 500 mg.
3. What is Triglypta-M 500 used for?
It is prescribed for the management of Type 2 Diabetes Mellitus and to help improve blood glucose control.
4. How does Dapagliflozin work?
Dapagliflozin reduces glucose reabsorption in the kidneys, resulting in increased urinary glucose excretion.
5. How does Sitagliptin work?
Sitagliptin inhibits DPP-4 and helps increase incretin activity, supporting glucose-dependent insulin secretion.
6. What is the role of Metformin?
Metformin primarily reduces glucose production by the liver and improves insulin sensitivity.
7. Can Triglypta-M 500 be taken without a doctor’s advice?
No. It should be taken only according to the prescription and guidance of a qualified healthcare professional.
8. Is Triglypta-M 500 suitable for all diabetes patients?
No. The suitability of this combination depends on individual factors such as existing treatment, kidney function, medical history and glycemic control. A doctor should determine whether it is appropriate.
9. Who markets Triglypta-M 500?
Triglypta-M 500 is marketed by Rapid Life Drugs & Healthcare.
